Adies syndrome definition of adies syndrome by medical. Argyll robertson pupil one that is miotic and responds to accommodation effort, but not to light. It is frequently seen in females with absent knee or ankle jerks and impaired sweating the syndrome is caused by damage to the postganglionic fibers of the. Syndrome pop culture when innocent heroworship goes unrequited, the consequences can be dire for both the admirer and the admired. A tonic pupil results from parasympathetic denervation at the level of the ciliary ganglion. This paper is an effort to unravel whether the tonic pupil and systemic sclerosis are an association by chance which may be the. Gli studi elettrofisiologici documentavano unassenza dei riflessi h con conduzioni periferiche conservate, e suggerivano una lesione a livello delle radici dorsali o del ganglio spinale, come riscontrato nei rari studi neuropatologici dimonstranti ganglionite dorsale. Adie syndrome, also known as holmesadie syndrome, is a neurological disorder characterized by a tonically dilated pupil that reacts slowly to light but shows a more definite response to accommodation i. Adie s tonic pupil in the differential diagnosis of neurologic syndromes with headache and anisocoria. Tonic pupils are unilateral in 80% of cases, although the second pupil may later become involved 4% per year. Holmes adie syndrome includes other features, notably diminished deep tendon reflexes and orthostatic hypotension. Holmesadie syndrome includes other features, notably diminished deep tendon reflexes and orthostatic hypotension.
A pupillary abnormality characterized by a poor pupillary light reaction, reduced accommodation, iris sector palsies, an enhanced pupillary response to near effort that results in a prolonged. All structured data from the file and property namespaces is available under the creative commons cc0 license. Sindrome di adie minerva oftalmologica 2007 september. Abstract the holmesadie syndrome is characterized by the presence of tonic pupil associated with absence or diminution of deep tendon reflexes. Adie tonic pupil american academy of ophthalmology. The tonic pupil, sometimes called adie tonic pupil or simply the adie pupil, is the term used to denote a pupil with parasympathetic denervation that constricts poorly to light but reacts better to accommodation near response, such that the initially larger adie pupil becomes smaller than its normal fellow and remains tonically constricted, redilating very slowly. Aminoff, in aminoffs neurology and general medicine fifth edition, 2014. Incredibles wannabe sidekick turned bad guy, from the incredibles 2004.
Argyll robertson pupil vs adies tonic pupil duration. Patients with holmes adie syndrome may present with or develop postural hypotension or abnormalities of thermoregulatory sweating. We even know something of how the nerves react after the damage is done, but we dont known what causes the primary injury. Currently, there are no specific methods or guidelines to prevent adie syndrome, since it is a genetic condition genetic counseling will help assess risks, before planning for a child. We report a rare association of adies tonic pupil in a patient with systemic sclerosis who was otherwise systemically stable. Pdf adies tonic pupil is a rare entity, which may be mistaken for other neurological. A tonic pupil is caused by postganglionic parasympathetic pupillomotor damage. Pdf adies tonic pupil in the differential diagnosis of neurologic. Rapd, relative afferent pupillary defect, marcusgunn pupil duration. We known where the damage is, and which nerves are involved. Adies pupil, sometimes called the holmesadie syndrome, is an unusual neurologic disorder in which the ability of the pupil to constrict is impaired, usually in one eye although the second eye has a tendency to become involved eventually, usually at a later time, in about 2030% of cases.
1370 841 791 1122 352 1396 1235 936 673 370 332 927 1237 969 123 36 95 47 334 1203 475 996 551 219 535 479 575 1301 396 1515 1610 886 124 1368 315 437 519 538 1184 772 496 1087 179